Infective Endocarditis: An Old But Changing Disease

Infective endocarditis (IE) is a severe form of valve disease characterized by infection located in the valves of the heart. It is still associated with a high mortality (10-26% in-hospital mortality). IE is a rare disease, with reported incidences ranging from 3 to 10 episodes/100,000 people per year. Previous guidelines were published in 2004.